HER-2/neu
protein overexpression by immunohistochemistry is an FDA approved test to
select patients for treatment with Herceptin® (Trastuzumab).
HER-2/neu oncogene
amplification by FISH is an FDA approved prognostic marker test for assessing
risk of breast cancer recurrence and disease related death.
Request either
test on a Surgical Pathology requisition form and provide an ICD-9 CM diagnostic
code.
You
may also submit a request by telephone at (313) 916-2308 or by e-mail at HER@LAB@hfhs.org.
Submit formalin
fixed paraffin block of breast cancer (or identify case number).
Routine turnaround
time is 7 days.
For
a discussion of results and special issues, call (313) 916-2308.